Publications of Werner Seeger

Turkowski, K.; Herzberg, F.; Guenther, S.; Weigert, A.; Haselbauer, T.; Fink, L.; Brunn, D.; Grimminger, F.; Seeger, W.; Sueltmann, H. et al.; Stiewe, T.; Pullamsetti, S. S.; Savai, R.: miR-147b mediated suppression of DUSP8 promotes lung cancer progression. ONCOGENE (2024)

Hirani, D. V.; Thielen, F.; Mansouri, S.; Danopoulos, S.; Vohlen, C.; Haznedar-Karakaya, P.; Mohr, J.; Wilke, R.; Selle, J.; Grosch, T. et al.; Mizik, I.; Odenthal, M.; Alvira, C. M.; Kuiper-Makris, C.; Pryhuber, G. S.; Pallasch, C.; van Koningsbruggen-Rietschel, S.; Al-Alam, D.; Seeger, W.; Savai, R.; Doetsch, J.; Alcazar, M. A. A.: CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia. INFLAMMATION AND REGENERATION 43 (1), 52 (2023)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), pp. 917 - + (2023)

Karger, A.; Mansouri, S.; Leisegang , M. S.; Weigert, A.; Guenther, S.; Kuenne, C.; Wittig , I.; Zukunft , S.; Klatt , S.; Aliraj , B. et al.; Klotz V , L.; Winter , H.; Mahavadi, P.; Fleming , I.; Ruppert , C.; Witte , B.; Alkoudmani , I.; Gattenloehner, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. EMBO JOURNAL (2023)

Alberro-Brage , A.; Kryvenko , V.; Malainou , C.; Guenther, S.; Morty, R. E.; Seeger, W.; Herold, S.; Samakovlis, C.; Vadasz, I.: Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells. FRONTIERS IN IMMUNOLOGY 14, 1260973 (2023)

Bandorski, D.; Tello, K.; Erdal, H.; Sommerlad, J.; Wilhelm, J.; Vadasz, I.; Hecker, M.; Walmrath, D.; Seeger, W.; Krauss, E. et al.; Kuhnert, S.: Clinical Utility of Pepsin and Bile Acid in Tracheal Secretions for Accurate Diagnosis of Aspiration in ICU Patients. JOURNAL OF CLINICAL MEDICINE 12 (17), 5466 (2023)

Zheng, X.; Sarode, P.; Weigert , A.; Turkowski, K.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Winter , H.; Stenzinger, A.; Reu, S. et al.; Grimminger, F.; Stiewe, T.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. CANCER RESEARCH 83 (14), pp. 2345 - 2357 (2023)

Steinbeis , F.; Thibeault , C.; Steinbrecher, S.; Ahlgrimm, Y.; Haack, I. A.; August, D.; Balzuweit, B.; Bellinghausen, C.; Berger, S.; Chaplinskaya-Sobol, I. et al.; Cornely, O.; Doeblin, P.; Endres, M.; Fink, C.; Finke, C.; Frank, S.; Hanss, S.; Hartung, T.; Hellmuth, J. C.; Herold, S.; Heuschmann, P.; Heyckendorf, J.; Heyder, R.; Hippenstiel, S.; Hoffmann, W.; Kelle, S. U.; Knape, P.; Koehler, P.; Kretzler, L.; Leistner, D. M.; Lienau, J.; Lorbeer, R.; Lorenz-Depiereux, B.; Luettke, C. D.; Mai, K.; Merle, U.; Meyer-Arndt, L. A.; Miljukov, O.; Muenchhoff, M.; Mueller-Plathe, M.; Neuhann, J.; Neuhauser, H.; Nieters, A.; Otte, C.; Pape, D.; Pinto, R. M.; Pley, C.; Pudszuhn, A.; Reuken, P.; Rieg, S.; Ritter, P.; Rohde, G.; Roennefarth, M.; Ruzicka, M.; Schaller, J.; Schmidt, A.; Schmidt, S.; Schwachmeyer, V.; Schwanitz, G.; Seeger, W.; Stahl, D.; Stobaeus, N.; Stubbe, H. C.; Suttorp, N.; Temmesfeld, B.; Thun, S.; Triller, P.; Trinkmann, F.; Vadasz, I.; Valentin, H.; Vehreschild, M.; von Kalle, C.; von Lilienfeld-Toal, M.; Weber, J.; Welte, T.; Wildberg, C.; Wizimirski, R.; Zvork, S.; Sander, L. E.; Vehreschild, J.; Zoller, T.; Kurth, F.; Witzenrath, M.: Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP). INFECTION (2023)

Roxlau, E. T.; Pak, O.; Hadzic, S.; Garcia-Castro, C. F.; Gredic, M.; Wu, C.-Y.; Schaeffer, J.; Selvakumar, B.; Pichl, A.; Spiegelberg, D. et al.; Deutscher, J.; Bednorz, M.; Schaefer, K.; Kraut, S.; Kosanovic, D.; Zeidan, E. M.; Kojonazarov, B.; Herold, S.; Strielkov, I.; Guenther, A.; Wilhelm, J.; Khalifa, M. M. A.; Taye, A.; Brandes, R. P.; Hecker, M.; Grimminger, F.; Ghofrani, H. A.; Schermuly, R. T.; Seeger, W.; Sommer, N.; Weissmann, N.: Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations. EUROPEAN RESPIRATORY JOURNAL 61 (6), 2200951 (2023)

Wu, C.-Y.; Cilic, A.; Pak, O.; Dartsch, R. C.; Wilhelm, J.; Wujak, M.; Lo, K.; Brosien, M.; Zhang, R.; Alkoudmani, I. et al.; Witte, B.; Pedersen, F.; Watz, H.; Voswinckel, R.; Unther, A. G.; Ghofrani, H. A.; Brandes, R. P.; Schermuly, R. T.; Grimminger, F.; Seeger, W.; Sommer, N.; Weissmann, N.; Hadzic, S.: CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 207 (12), pp. 1576 - 1590 (2023)

Nayakanti, S. R.; Friedrich, A.; Sarode, P.; Jafari, L.; Maroli, G.; Boehm, M.; Bourgeois, A.; Grobs, Y.; Khassafi, F.; Kuenne, C. et al.; Guenther, S.; Dabral, S.; Wilhelm, J.; Weiss, A.; Wietelmann, A.; Kojonazarov, B.; Janssen, W.; Looso, M.; de Man, F.; Provencher, S.; Tello, K.; Seeger, W.; Bonnet, S.; Savai, R.; Schermuly, R.; Pullamsetti, S. S.: Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling. CIRCULATION RESEARCH 132 (11), pp. 1468 - 1485 (2023)

Wasnick, R.; Korfei, M.; Piskulak, K.; Henneke, I.; Wilhelm, J.; Mahavadi, P.; Dartsch, R. C.; von der Beck, D.; Koch, M.; Shalashova, I. et al.; Weiss, A.; Klymenko, O.; Askevold, I.; Fink, L.; Witt, H.; Hackstein, H.; El Agha, E.; Bellusci, S.; Klepetko, W.; Koenigshoff, M.; Eickelberg, O.; Schermuly, R. T.; Braun, T.; Seeger, W.; Ruppert, C.; Guenther, A.: Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 27 (3), pp. 283 - 299 (2023)

Kryvenko, V.; Alberro-Brage, A.; Fysikopoulos, A.; Wessendorf, M.; Tello, K.; Morty, R. E.; Herold, S.; Seeger, W.; Samakovlis, C.; Vadasz, I.: Clathrin-Mediated Albumin Clearance in Alveolar Epithelial Cells of Murine Precision-Cut Lung Slices. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24 (3), 2644 (2023)

Gredic, M.; Sharma, V.; Hadzic, S.; Wu, C.-Y.; Pak, O.; Kojonazarov, B.; Duerr, J.; Mall, M. A. A.; Guenther, A.; Schermuly, R. T. T. et al.; Grimminger, F.; Seeger, W.; Kraut, S.; Sommer, N.; Weissmann, N.: iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice. CELLS 12 (1), 125 (2022)

Sauer, A.; Seeliger, B.; Jandl, K.; Erfinanda, L.; Wilhelm, J.; Alexopoulos, I.; Baal, N.; Birnhuber, A.; David, S.; Welte, T. et al.; Barreto, G.; Gaertner, U.; Kwapiszewska, G.; Seeger, W.; Kuebler, W. M.; Schaefer, L.; Wygrecka, M.: Circulating hyaluronic acid signature in CAP and ARDS- the role of pneumolysin in hyaluronic acid shedding. MATRIX BIOLOGY 114, pp. 67 - 83 (2022)

Chu, X.; Lingampally, A.; Moiseenko, A.; Kheirollahi, V.; Vazquez-Armendariz, A. I.; Koepke, J.; Khadim, A.; Kiliaris, G.; Felordi, M. S.; Zabihi, M. et al.; Shalashova, I.; Alexopoulos, I.; Guenther, S.; Lebrigand, K.; Truchi, M.; Guenther, A.; Braun, T.; Mari, B.; Samakovlis, C.; Li, X.; Seeger, W.; Herold, S.; Zhang, J.-S.; Bellusci, S.; El Agha, E.: GLI1+cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. CELLULAR AND MOLECULAR LIFE SCIENCES 79 (11), 581 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Kimmig, L. M.; Rako, Z. A.; Ziegler, S.; Richter, M. J.; Tolou, A. G. S.; Roller, F.; Grimminger, F.; Vadasz, I.; Seeger, W.; Herold, S. et al.; Tello, K.; Matt, U.: Long-term comprehensive cardiopulmonary phenotyping of COVID-19. RESPIRATORY RESEARCH 23 (1), 263 (2022)

Rai, N.; Sydykov, A.; Kojonazarov, B.; Wilhelm, J.; Manaud, G.; Veeroju, S.; Ruppert, C.; Perros, F.; Ghofrani, H. A.; Weissmann, N. et al.; Seeger, W.; Schermuly, R. T.; Novoyatleva, T.: Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension. EUROPEAN RESPIRATORY JOURNAL 60 (2), 2101698 (2022)

Selle, J.; Dinger, K.; Jentgen, V.; Zanetti, D.; Will, J.; Georgomanolis, T.; Vohlen, C.; Wilke, R.; Kojonazarov, B.; Klymenko, O. et al.; Mohr, J.; Koningsbruggen-Rietschel, S. v.; Rhodes, C. J.; Ulrich, A.; Hirani, D.; Nestler, T.; Odenthal, M.; Mahabir, E.; Nayakanti, S.; Dabral, S.; Wunderlich, T.; Priest, J.; Seeger, W.; Doetsch, J.; Pullamsetti, S. S.; Alcazar, M. A. A.: Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. NATURE COMMUNICATIONS 13 (1), 4352 (2022)