Publications of IMPRS students

Weiss, L. M.; Warwick, T.; Zehr, S.; Guenther, S.; Wolf, S.; Schmachtel, T.; Ponce, J. I.; Palfi, K.; Teichmann, T.; Schneider, A. et al.; Stoetzel, J.; Knapp, S.; Weigert, A.; Savai, R.; Rieger, M. A.; Oellerich, T.; Wittig, I.; Oo, J. A.; Brandes, R. P.; Leisegang, M. S.: RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions. COMMUNICATIONS BIOLOGY 7 (1), 1131 (2024)

Ozaki, K.; Kato, R.; Yasuhara, T.; Uchihara, Y.; Hirakawa, M.; Abe, Y.; Shibata, H.; Kawabata-Iwakawa, R.; Shakayeva, A.; Kot, P. et al.; Miyagawa, K.; Suzuki, K.; Matsuda, N.; Shibata, A.; Yamauchi, M.: Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks. SCIENTIFIC REPORTS 14 (1), 18455 (2024)

Maroli, G.; Scha, A.; Guenther, S.; -Gonzalez, C. G.; Rupp, S.; Schlierbach, H.; Chen, Y.; Graumann, J.; Wietelmann, A.; Kim, J. et al.; Braun, T.: Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 193, pp. 53 - 66 (2024)

Peng, Y.; Du, J.; Li, R.; Guenther, S.; Wettschureck, N.; Offermanns, S.; Wang, Y.; Schneider, A.; Braun, T.: RhoA-mediated G₁₂-G₁₃ signaling maintains muscle stem cell quiescence and prevents stem cell loss. CELL DISCOVERY 10 (1), 76 (2024)

Gentile, A.; Albu, P. M.; Xu, Y.; Mortazavi , N.; da Silva, A.; Stainier, D. Y. R.; Gunawan, F.: Mechanical forces remodel the cardiac extracellular matrix during zebrafish development. DEVELOPMENT 151 (13), dev202310 (2024)

Kumari, P.; Tarighi, S.; Fuchshuber, E.; Li, L.; Fernandez-Duran, I.; Wang, M.; Ayoson, J.; Castello-Garcia, J. M.; Gamez-Garcia, A.; Espinosa-Alcantud, M. et al.; Sreenivasan, K.; Guenther, S.; Olivella, M.; Savai, R.; Yue, S.; Vaquero, A.; Braun, T.; Ianni, A.: SIRT7 promotes lung cancer progression by destabilizing the tumor suppressor ARF. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 121 (25), e2409269121 (2024)

Zhu, Y.; Ackers-Johnson, M.; Shanmugam, M. K.; Pakkiri, L. S.; Drum, C. L.; Chen, Y.; Kim, J.; Paltzer, W. G.; Mahmoud, A. I.; Tan, W. L. W. et al.; Lee, M. C. J.; Jiang, J.; Luu, D. A. T.; Ng, S. L.; Li, P. Y. Q.; Wang, A.; Qi, R.; Ong, G. J. X.; Ng, T. Y.; Haigh, J. J.; Tiang, Z.; Richards, A. M.; Foo, R. S. Y.: Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation. CIRCULATION 149 (23), pp. 1833 - 1851 (2024)

Gauvrit, S.; Zhao, S.; Rothbauer, U.; Stainier, D. Y. R.: A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo. DEVELOPMENT 151 (11), dev202122 (2024)

Brunnberg, J.; Barends, M.; Fruehschulz, S.; Winter, C.; Battin, C.; de Wet, B.; Cole, D. K.; Steinberger, P.; Tampe, R.: Dual role of the peptide- loading complex as proofreader and limiter of MHC- I presentation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 121 (22), e2321600121 (2024)

Ribeiro da Silva, A.; Gunawan, F.; Boezio, G. L. M.; Faure , E.; Theron , A.; Avierinos , J.-F.; Lim, S.; Shivam, G. J.; Ramadass, R.; Guenther, S. et al.; Looso, M.; Zaffran, S.; Juan, T.; Stainier, D. Y. R.: egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis. SCIENCE ADVANCES 10 (20), eadl0633 (2024)

Tamiato, A.; Tombor, L. S.; Fischer, A.; Muhly-Reinholz, M.; Vanicek, L. R.; Togru, B. N.; Neitz, J.; Glaser, S. F.; Merten, M.; Morales, D. R. et al.; Kwon, J.; Klatt, S.; Schumacher, B.; Guenther, S.; Abplanalp, W. T.; John, D.; Fleming, I.; Wettschureck, N.; Dimmeler, S.; Luxaen, G.: Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. CIRCULATION RESEARCH 134 (10), pp. 1240 - 1255 (2024)

Wang, T.; Shao, J.; Shamit, K.; Alnouri, M. W.; Carvalho, J.; Guenther, S.; Krasel , C.; Murphy, K. T.; Buenemann, M.; Offermanns, S. et al.; Wettschureck, N.: Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction. CIRCULATION RESEARCH 134 (10), pp. 1259 - 1275 (2024)

Vega-Sendino, M.; Luettmann, F. F.; Olbrich, T.; Chen, Y.; Kuenne, C.; Stein, P.; Tillo, D.; Carey, G. I.; Zhong, J.; Savy, V. et al.; Radonova, L.; Lu, T.; Saykali, B.; Kim, K.-P.; Domingo, C. N.; Schueler, L.; Guenther, S.; Bentsen, M.; Bosnakovski, D.; Schoeler, H.; Kyba, M.; Maity, T. K.; Jenkins, L. M.; Looso, M.; Williams, C. J.; Kim, J.; Ruiz, S.: The homeobox transcription factor DUXBL controls exit from totipotency. NATURE GENETICS (56), pp. 697 - 709 (2024)

Teichmann, T.; Malacarne, P.; Zehr, S.; Guenther, S.; Pflueger-Mueller, B.; Warwick, T.; Brandes, R. P.: NCoR1 limits angiogenic capacity by altering Notch signaling. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 188, pp. 65 - 78 (2024)

Ianni, A.; Kumari, P.; Tarighi, S.; Braun, T.; Vaquero, A.: SIRT7: a novel molecular target for personalized cancer treatment? ONCOGENE (2024)

Vazquez, B. N.; Fernandez-Duran, I.; Hernandez, Y.; Tarighi, S.; Thackray, J. K.; Espinosa-Alcantud, M.; Kumari, P.; Ianni, A.; Cesaire, L.; Braun, T. et al.; Esteller, M.; Tischfield, J.; Vaquero, A.; Serrano, L.: SIRT7 and p53 interaction in embryonic development and tumorigenesis. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 11, 1281730 (2024)

Weiss, M.; Hettrich, S.; Hofmann, T.; Hachim, S.; Guenther, S.; Braun, T.; Boettger, T.: Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH. NUCLEIC ACIDS RESEARCH (2024)

Wu, F.; Li, X.; Looso, M.; Liu, H.; Ding, D.; Guenther, S.; Kuenne, C.; Liu, S.; Weissmann, N.; Boettger, T. et al.; Atzberger, A.; Kolahian, S.; Renz, H.; Offermanns, S.; Gaertner, U.; Potente, M.; Zhou, Y.; Yuan, X.; Braun, T.: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. NATURE GENETICS 55 (1), pp. 100 - + (2024)

Latimer, M. N.; Williams, L. J.; Shanmugan, G.; Carpenter, B.; Lazar, M. A.; Dierickx, P.; Young, M. E.: Cardiomyocyte-specific disruption of the circadian BMAL1-REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart. COMMUNICATIONS BIOLOGY 6 (1), 1149 (2023)

Bonnavion, R.; Liu, S.; Kawase, H.; Roquid, K. A.; Offermanns, S.: Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5). FRONTIERS IN PHARMACOLOGY 14, 1297596 (2023)

Hu, J.; Leisegang, M. S.; Looso, M.; Drekolia, M.-K.; Wittig, J.; Mettner, J.; Karantanou, C.; Kyselova, A.; Dumbovic, G.; Li, X. et al.; Li, Y.; Guenther, S.; John, D.; Siragusa, M.; Zukunft, S.; Oo, J.; Wittig, I.; Hille, S.; Weigert, A.; Knapp, S.; Brandes, R. P.; Muller, O. J.; Papapetropoulos, A.; Sigala, F.; Dobreva, G.; Kojonazarov, B.; Fleming, I.; Bibli, S.-I.: Disrupted Binding of Cystathionine gamma-Lyase to p53 Promotes Endothelial Senescence. Circulation research (2023)

Farin, H. F.; Mosa, M. H.; Ndreshkjana, B.; Grebbin, B. M.; Ritter, B.; Menche, C.; Kennel, K. B.; Ziegler, P. K.; Szabo, L.; Bollrath, J. et al.; Rieder, D.; Michels, B. E.; Kress, A.; Bozlar, M.; Darvishi, T.; Stier, S.; Kur, I.-M.; Bankov, K.; Kesselring, R.; Fichtner-Feigl, S.; Bruene, B.; Goetze, T. O.; Al-Batran, S.-E.; Brandts, C. H.; Bechstein, W. O.; Wild, P. J.; Weigert, A.; Mueller, S.; Knapp, S.; Trajanoski, Z.; Greten, F. R.: Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses. CANCER DISCOVERY 13 (10), pp. 2192 - 2211 (2023)

Li, X.; Wu, F.; Guenther, S.; Looso, M.; Kuenne, C.; Zhang, T.; Wiesnet, M.; Klatt, S.; Zukunft, S.; Fleming, I. et al.; Poschet, G.; Wietelmann, A.; Atzberger, A.; Potente, M.; Yuan, X.; Braun, T.: Inhibition of fatty acid oxidation enables heart regeneration in adult mice. NATURE (2023)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), pp. 917 - + (2023)

Ehret, E.; Stroh, S.; Auberson, M.; Ino, F.; Jager, Y.; Maillard, M.; Szabo, R.; Bugge, T. H.; Frateschi, S.; Hummler, E.: Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity. CELLS 12 (19), 2342 (2023)