Publications of IMPRS students

Selle, J.; Dinger, K.; Jentgen, V.; Zanetti, D.; Will, J.; Georgomanolis, T.; Vohlen, C.; Wilke, R.; Kojonazarov, B.; Klymenko, O. et al.; Mohr, J.; Koningsbruggen-Rietschel, S. v.; Rhodes, C. J.; Ulrich, A.; Hirani, D.; Nestler, T.; Odenthal, M.; Mahabir, E.; Nayakanti, S.; Dabral, S.; Wunderlich, T.; Priest, J.; Seeger, W.; Doetsch, J.; Pullamsetti, S. S.; Alcazar, M. A. A.: Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. NATURE COMMUNICATIONS 13 (1), 4352 (2022)

Hu, B.; Lelek, S.; Spanjaard, B.; El-Sammak, H.; Simoes, M. G.; Mintcheva, J.; Aliee, H.; Schaefer, R.; Meyer, A. M.; Theis, F. et al.; Stainier, D. Y. R.; Panakova, D.; Junker, J. P.: Origin and function of activated fibroblast states during zebrafish heart regeneration. NATURE GENETICS (2022)

Georgieva, A. M.; Guo, X.; Bartkuhn, M.; Guenther, S.; Kuenne, C.; Smolka, C.; Atzberger, A.; Gaertner, U.; Mamchaoui, K.; Bober, E. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. NATURE COMMUNICATIONS 13 (1), 4184 (2022)

Xu, R.; Hoess, C.; Swiercz, J. M.; Brandt, D. T.; Lutz, V.; Petersen, N.; Li, R.; Zhao, D.; Oleksy, A.; Creigh-Pulatmen, T. et al.; Trokter, M.; Fedorova, M.; Atzberger, A.; Strandby, R. B.; Olsen, A. A.; Achiam, M. P.; Matthews, D.; Huber, M.; Groene, H.-J.; Offermanns, S.; Worzfeld, T.: A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers. SCIENCE TRANSLATIONAL MEDICINE 14 (654), eabf1922 (2022)

Ehret, E.; Jaeger, Y.; Sergi, C.; Merillat, A.-M.; Peyrollaz, T.; Anand, D.; Wang, Q.; Ino, F.; Maillard, M.; Kellenberger, S. et al.; Gautschi, I.; Szabo, R.; Bugge, T. H.; Vogel, L. K.; Hummler, E.; Frateschi, S.: Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (12), 6745 (2022)

Klockner, I.; Schutt, C.; Gerhardt, T.; Boettger, T.; Braun, T.: Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. NATURE COMMUNICATIONS 13 (1), 3180 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Mueller, N.; Lopez, M.; Pflueger-Mueller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Guenther, S.; Weigert, A.; Geisslinger, G.; Luetjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. HYPERTENSION 79 (6), pp. 1216 - 1226 (2022)

Liang, G.; Wang, S.; Shao, J.; Jin, Y.-J.; Xu, L.; Yan, Y.; Guenther, S.; Wang, L.; Offermanns, S.: Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. CIRCULATION RESEARCH 130 (11), pp. 1647 - 1659 (2022)

Malacarne, P. F.; Bezzenberger, J.; Lopez, M.; Warwick, T.; Mueller, N.; Brandes, R. P.; Rezende, F.: Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (11), 5939 (2022)

Chu, Z.; Gu, L.; Hu, Y.; Zhang, X.; Li, M.; Chen, J.; Teng, D.; Huang, M.; Shen, C.-H.; Cai, L. et al.; Yoshida, T.; Qi, Y.; Niu, Z.; Feng, A.; Geng, S.; Frederick, D. T.; Specht, E.; Piris, A.; Sullivan, R. J.; Flaherty, K. T.; Boland, G. M.; Georgopoulos, K.; Liu, D.; Shi, Y.; Zheng, B.: STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. NATURE COMMUNICATIONS 13 (1), 1859 (2022)

Yang, Y. H. C.; Briant, L. J. B.; Raab, C. A.; Mullapudi, S. T.; Maischein, H.-M.; Kawakami, K.; Stainier, D. Y. R.:

Innervation modulates the functional connectivity between pancreatic endocrine cells

. ELIFE 11, e64526 (2022)

Peng, Y.; Du, J.; Gunther, S.; Guo, X.; Wang, S.; Schneider, A.; Zhu, L.; Braun, T.: Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells. REDOX BIOLOGY 52, 102309 (2022)

El-Sammak, H.; Yang, B.; Guenther, S.; Chen, W.; Marin-Juez, R.; Stainier, D. Y. R.: A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. CIRCULATION RESEARCH 130 (7), pp. 1014 - 1029 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, pp. 1023 - 1035 (2022)

Keshavarz, M.; Tabrizi, S. F.; Ruppert, A.-L.; Pfeil, U.; Schreiber, Y.; Klein, J.; Brandenburger, I.; Lochnit, G.; Bhushan, S.; Perniss, A. et al.; Deckmann, K.; Hartmann, P.; Meiners, M.; Mermer, P.; Rafiq, A.; Winterberg, S.; Papadakis, T.; Thomas, D.; Angioni, C.; Oberwinkler, J.; Chubanov, V.; Gudermann, T.; Gaertner, U.; Offermanns, S.; Schuetz, B.; Kummer, W.: Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. SCIENCE IMMUNOLOGY 7 (69), eabf6734 (2022)

Qi, J.; Rittershaus, A.; Priya, R.; Mansingh, S.; Stainier, D. Y. R.; Helker, C. S. M.; Bautch, V. L.: Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish. ELIFE 11, e73231 (2022)

Muller, N.; Warwick, T.; Noack, K.; Malacarne, P. F.; Cooper, A. J. L.; Weissmann, N.; Schroder, K.; Brandes, R. P.; Rezende, F.: Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Antioxidants (Basel, Switzerland) 11 (2), p. 434 (2022)

Heumueller, A. W.; Jones, A. N.; Mourao, A.; Klangwart, M.; Shi, C.; Wittig, I.; Fischer, A.; Muhly-Reinholz, M.; Buchmann, G. K.; Dieterich, C. et al.; Potente, M.; Braun, T.; Grote, P.; Jae, N.; Sattler, M.; Dimmeler, S.: Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses. CIRCULATION RESEARCH 130 (1), pp. 67 - 79 (2022)

Hahner, F.; Moll, F.; Warwick, T.; Hebchen, D. M.; Buchmann, G. K.; Epah, J.; Abplanalp, W.; Schader, T.; Gunther, S.; Gilsbach, R. et al.; Brandes, R. P.; Schroder, K.: Nox4 promotes endothelial differentiation through chromatin remodeling. Redox biology 55, 102381 (2022)

Koller, N.; Hollthaler, P.; Barends, M.; Doring, M.; Spahn, C.; Duran, V.; Costa, B.; Becker, J.; Heilemann, M.; Kalinke, U. et al.; Tampe, R.: Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells. Cellular and molecular life sciences: CMLS 79 (9), 477 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Muller, N.; Lopez, M.; Pfluger-Muller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Gunther, S.; Weigert, A.; GeiSSlinger, G.; Lutjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (Dallas, Tex.: 1979) (2022)

Ong, Y. T.; Andrade, J.; Armbruster, M.; Shi, C.; Castro, M.; Costa, A. S. H.; Sugino, T.; Eelen, G.; Zimmermann, B.; Wilhelm, K. et al.; Lim, J.; Watanabe, S.; Guenther, S.; Schneider, A.; Zanconato, F.; Kaulich, M.; Pan, D.; Braun, T.; Gerhardt, H.; Efeyan, A.; Carmeliet, P.; Piccolo, S.; Grosso, A. R.; Potente, M.: A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. NATURE METABOLISM 4 (6), pp. 672 - 682 (2022)

Warwick, T.; Schulz, M. H.; Gilsbach, R.; Brandes, R. P.; Seuter, S.: Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Nucleic acids research (2022)

Tarasco, M.; Gavaia, P. J.; Bensimon-Brito, A.; Cardeira-da-Silva, J.; Ramkumar, S.; Cordelieres, F. P.; Guenther, S.; Bebianno, M. J.; Stainier, D. Y. R.; Cancela, M. L. et al.; Laize, V.: New insights into benzo[alpha]pyrene osteotoxicity in zebrafish. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 226, 112838 (2021)

Sarvari, P.; Rasouli, S. J.; Allanki, S.; Stone, O. A.; Sokol, A. M.; Graumann, J.; Stainier, D. Y. R.: The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish. DEVELOPMENTAL BIOLOGY 480, pp. 1 - 12 (2021)