Publications of IMPRS students

Chu, Z.; Gu, L.; Hu, Y.; Zhang, X.; Li, M.; Chen, J.; Teng, D.; Huang, M.; Shen, C.-H.; Cai, L. et al.; Yoshida, T.; Qi, Y.; Niu, Z.; Feng, A.; Geng, S.; Frederick, D. T.; Specht, E.; Piris, A.; Sullivan, R. J.; Flaherty, K. T.; Boland, G. M.; Georgopoulos, K.; Liu, D.; Shi, Y.; Zheng, B.: STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. NATURE COMMUNICATIONS 13 (1), 1859 (2022)

Yang, Y. H. C.; Briant, L. J. B.; Raab, C. A.; Mullapudi, S. T.; Maischein, H.-M.; Kawakami, K.; Stainier, D. Y. R.:

Innervation modulates the functional connectivity between pancreatic endocrine cells

. ELIFE 11, e64526 (2022)

El-Sammak, H.; Yang, B.; Guenther, S.; Chen, W.; Marin-Juez, R.; Stainier, D. Y. R.: A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. CIRCULATION RESEARCH 130 (7), pp. 1014 - 1029 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, pp. 1023 - 1035 (2022)

Keshavarz, M.; Tabrizi, S. F.; Ruppert, A.-L.; Pfeil, U.; Schreiber, Y.; Klein, J.; Brandenburger, I.; Lochnit, G.; Bhushan, S.; Perniss, A. et al.; Deckmann, K.; Hartmann, P.; Meiners, M.; Mermer, P.; Rafiq, A.; Winterberg, S.; Papadakis, T.; Thomas, D.; Angioni, C.; Oberwinkler, J.; Chubanov, V.; Gudermann, T.; Gaertner, U.; Offermanns, S.; Schuetz, B.; Kummer, W.: Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. SCIENCE IMMUNOLOGY 7 (69), eabf6734 (2022)

Muller, N.; Warwick, T.; Noack, K.; Malacarne, P. F.; Cooper, A. J. L.; Weissmann, N.; Schroder, K.; Brandes, R. P.; Rezende, F.: Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Antioxidants (Basel, Switzerland) 11 (2), p. 434 (2022)

Heumueller, A. W.; Jones, A. N.; Mourao, A.; Klangwart, M.; Shi, C.; Wittig, I.; Fischer, A.; Muhly-Reinholz, M.; Buchmann, G. K.; Dieterich, C. et al.; Potente, M.; Braun, T.; Grote, P.; Jae, N.; Sattler, M.; Dimmeler, S.: Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses. CIRCULATION RESEARCH 130 (1), pp. 67 - 79 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Muller, N.; Lopez, M.; Pfluger-Muller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Gunther, S.; Weigert, A.; GeiSSlinger, G.; Lutjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (Dallas, Tex.: 1979) (2022)

Warwick, T.; Schulz, M. H.; Gilsbach, R.; Brandes, R. P.; Seuter, S.: Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Nucleic acids research (2022)

Tarasco, M.; Gavaia, P. J.; Bensimon-Brito, A.; Cardeira-da-Silva, J.; Ramkumar, S.; Cordelieres, F. P.; Guenther, S.; Bebianno, M. J.; Stainier, D. Y. R.; Cancela, M. L. et al.; Laize, V.: New insights into benzo[alpha]pyrene osteotoxicity in zebrafish. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 226, 112838 (2021)

Sarvari, P.; Rasouli, S. J.; Allanki, S.; Stone, O. A.; Sokol, A. M.; Graumann, J.; Stainier, D. Y. R.: The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish. DEVELOPMENTAL BIOLOGY 480, pp. 1 - 12 (2021)

Gurusamy, M.; Tischner, D.; Shao, J.; Klatt, S.; Zukunft, S.; Bonnavion, R.; Guenther, S.; Siebenbrodt, K.; Kestner, R.-I.; Kuhlmann, T. et al.; Fleming, I.; Offermanns, S.; Wettschureck, N.: G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS 12 (1), 6798 (2021)

Ando, K.; Shih, Y.-H.; Ebarasi, L.; Grosse, A.; Portman, D.; Chiba, A.; Mattonet, K.; Gerri, C.; Stainier, D. Y. R.; Mochizuki, N. et al.; Fukuhara, S.; Betsholtz, C.; Lawson, N. D.: Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development. DEVELOPMENTAL BIOLOGY 479, pp. 11 - 22 (2021)

Jin, Y.-J.; Chennupati, R.; Li, R.; Liang, G.; Wang, S.; Iring, A.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION 131 (21), e145734 (2021)

Cremer, S.; Pilgram, L.; Berkowitsch, A.; Stecher, M.; Rieg, S.; Shumliakivska, M.; Bojkova, D.; Wagner, J. U. G.; Aslan, G. S.; Spinner, C. et al.; Luxan, G.; Hanses, F.; Dolff, S.; Piepel, C.; Ruppert, C.; Guenther, A.; Ruthrich, M. M.; Vehreschild, J. J.; Wille, K.; Haselberger, M.; Heuzeroth, H.; Hansen, A.; Eschenhagen, T.; Cinatl, J.; Ciesek, S.; Dimmeler, S.; Borgmann, S.; Zeiher, A.: Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease. PLOS ONE 16 (10), e0258684 (2021)

Cremer, S.; Pilgram, L.; Berkowitsch, A.; Stecher, M.; Rieg, S.; Shumliakivska, M.; Bojkova, D.; Wagner, J. U. G.; Aslan, G. S.; Spinner, C. et al.; Luxan, G.; Hanses, F.; Dolff, S.; Piepel, C.; Ruppert, C.; Guenther, A.; Ruthrich, M. M.; Vehreschild, J. J.; Wille, K.; Haselberger, M.; Heuzeroth, H.; Hansen, A.; Eschenhagen, T.; Cinatl, J.; Ciesek, S.; Dimmeler, S.; Borgmann, S.; Zeiher, A.: Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease. PLOS ONE 16 (10), e0258684 (2021)

Yekelchyk, M.; Madan, E.; Wilhelm, J.; Short, K. R.; Liao, L.; Camacho, D.; Nkadori, E.; Winters, M. T.; Rice, E. S.; Rolim, I. et al.; Cruz-Duarte, R.; Pelham, C. J.; Nagane, M.; Gupta, K.; Chaudhary, S.; Braun, T.; Pillappa, R.; Parker, M. S.; Menter, T.; Matter, M.; Haslbauer, J. D.; Tolnay, M.; Galior, K. D.; Matkwoskyj, K. A.; McGregor, S. M.; Muller, L. K.; Rakha, E. A.; Lopez-Beltran, A.; Drapkin, R.; Ackermann, M.; Fisher, P. B.; Grossman, S. R.; Godwin, A. K.; Kulasinghe, A.; Martinez, I.; Marsh, C. B.; Tang, B.; Wicha, M. S.; Won, K. J.; Tzankov, A.; Moreno, E.; Gogna, R.: Flower lose, a cell fitness marker, predicts COVID-19 prognosis. EMBO MOLECULAR MEDICINE, e13714 (2021)

Valussi, M.; Besser, J.; Wystub-Lis, K.; Zukunft, S.; Richter, M.; Kubin, T.; Boettger, T.; Braun, T.: Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. SCIENCE ADVANCES 7 (42), eabi6648 (2021)

Bensimon-Brito, A.; Boezio, G. L. M.; Cardeira-da-Silva, J.; Wietelmann, A.; Ramkumar, S.; Lundegaard, P. R.; Helker, C. S. M.; Ramadass, R.; Piesker, J.; Nauerth, A. et al.; Mueller, C.; Stainier, D. Y. R.: Integration of multiple imaging platforms to uncover cardiovascular defects in adult zebrafish. CARDIOVASCULAR RESEARCH, cvab310 (2021)

Qi, H.; Liu, H.; Pullamsetti, S. S.; Gunther, S.; Kuenne, C.; Atzberger, A.; Sommer, N.; Hadzic, S.; Gunther, A.; Weissmann, N. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. CIRCULATION 144 (13), pp. 1042 - 1058 (2021)

Chen, Y.; Luttmann, F. F.; Schoger, E.; Schoeler, H. R.; Zelarayan, L. C.; Kim, K.-P.; Haigh, J. J.; Kim, J.; Braun, T.: Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice. SI 373 (6562), pp. 1537 - 1540 (2021)

Allanki, S.; Strilic, B.; Scheinberger, L.; Onderwater, Y. L.; Marks, A.; Guenther, S.; Preussner, J.; Kikhi, K.; Looso, M.; Stainier, D. Y. R. et al.; Reischauer, S.: Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. SCIENCE ADVANCES 7 (37), eabg6497 (2021)

Buchmann, G. K.; Schurmann, C.; Spaeth, M.; Abplanalp, W.; Tombor, L.; John, D.; Warwick, T.; Rezende, F.; Weigert, A.; Shah, A. M. et al.; Hansmann, M.-L.; Weissmann, N.; Dimmeler, S.; Schroder, K.; Brandes, R. P.: The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice. Redox biology 45, p. 102050 - 102050 (2021)

Kumari, P.; Tarighi, S.; Braun, T.; Ianni, A.: SIRT7 Acts as a Guardian of Cellular Integrity by Controlling Nucleolar and Extra-Nucleolar Functions. GENES 12 (9), 1361 (2021)

Karger, A.; Nandigama, R.; Stenzinger, A.; Grimminger, F.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Hidden Treasures: Macrophage Long Non-Coding RNAs in Lung Cancer Progression. CANCERS 13 (16), 4127 (2021)