Publications of IMPRS students

Gatsiou, A.; Vlachogiannis, N.; Lunella, F. F.; Sachse, M.; Stellos, K.: Adenosine-to-Inosine RNA Editing in Health and Disease. ANTIOXIDANTS & REDOX SIGNALING 29 (9), pp. 846 - 863 (2018)

Vasconez, A. E.; Janetzko, P.; Oo, J. A.; Pflueger-Mueller, B.; Ratiu, C.; Gu, L.; Helin, K.; Geisslinger, G.; Fleming, I.; Schroeder, K. et al.; Fork, C.; Brandes, R. P.; Leisegang, M. S.: The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3 ' UTR of soluble epoxide hydrolase. ACTA PHYSIOLOGICA 225 (1), e13168 (2018)

Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S. I.; Li, X.; Zukunft, S.; Pflueger, B.; Hu, J.; Schuermann, C.; Vasconez, A. E. et al.; Oo, J. A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C. E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A. J.; Namgaladze, D.; Fleming, I.; Leisegang, M. S.; Zhu, J.; Brandes, R. P.: Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. NATURE COMMUNICATIONS 9, 2292 (2018)

Albarran-Juarez, J.; Iring, A.; Wang, S.; Joseph, S.; Grimm, M.; Strilic, B.; Wettschureck, N.; Althoff, T. F.; Offermanns, S.: Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation. JOURNAL OF EXPERIMENTAL MEDICINE 215 (10), pp. 2655 - 2672 (2018)

Astone, M.; Lai, J. K. H.; Dupont, S.; Stainier, D. Y. R.; Argenton, F.; Vettori, A.: Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. SCIENTIFIC REPORTS 8, 10189 (2018)

Boskovic, S.; Marin-Juez, R.; Jasnic, J.; Reischauer, S.; El Sammak, H.; Kojic, A.; Faulkner, G.; Radojkovic, D.; Stainier, D. Y. R.; Kojic, S.: Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLOS ONE 13 (9), e0204312 (2018)

Burg, L.; Palmer, N.; Kikhi, K.; Miroshnik, E. S.; Rueckert, H.; Gaddy, E.; Cunningham, C. M.; Mattonet, K.; Lai, S.-L.; Marin-Juez, R. et al.; Waring, R. B.; Stainier, D. Y. R.; Balciunas, D.: Conditional mutagenesis by oligonucleotide-mediated integration of loxP sites in zebrafish. PLOS GENETICS 14 (11), e1007754 (2018)

Ceci, M.; Carlantoni, C.; Missinato, M. A.; Bonvissuto, D.; Di Giacomo, B.; Contu, R.; Romano, N.: Micro RNAs are involved in activation of epicardium during zebrafish heart regeneration. CELL DEATH DISCOVERY 4, 41 (2018)

Gerri, C.; Marass, M.; Rossi, A.; Stainier, D. Y. R.: Hif-1 alpha and Hif-2 alpha regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. BLOOD 131 (9), pp. 963 - 973 (2018)

Herz, K.; Becker, A.; Shi, C.; Ema, M.; Takahashi, S.; Potente, M.; Hesse, M.; Fleischmann, B. K.; Wenzel, D.: Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system. ANGIOGENESIS 21 (2), pp. 349 - 361 (2018)

Hikita, T.; Mirzapourshafiyi, F.; Barbacena, P.; Riddell, M.; Pasha, A.; Li, M.; Kawamura, T.; Brandes, R. P.; Hirose, T.; Ohno, S. et al.; Gerhardt, H.; Matsuda, M.; Franco, C. A.; Nakayama, M.: PAR-3 controls endothelial planar polarity and vascular inflammation under laminar flow. EMBO REPORTS 19 (9), e45253 (2018)

Jia, G.; Preussner, J.; Chen, X.; Guenther, S.; Yuan, X.; Yekelchyk, M.; Kuenne, C.; Looso, M.; Zhou, Y.; Teichmann, S. et al.; Braun, T.: Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement. NATURE COMMUNICATIONS 9, 4877 (2018)

Lai, J. K. H.; Collins, M. M.; Uribe, V.; Jimenez-Amilburu, V.; Guenther, S.; Maischein, H.-M.; Stainier, D. Y. R.: The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. DEVELOPMENT 145 (10), UNSP dev159210 (2018)

Loerchner, H.; Hou, Y.; Adrian-Segarra, J. M.; Kulhei, J.; Detzer, J.; Guenther, S.; Gajawada, P.; Warnecke, H.; Niessen, H. W.; Poeling, J. et al.; Braun, T.: Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction. CARDIOVASCULAR RESEARCH 114 (12), pp. 1667 - 1679 (2018)

Ma, L.-S.; Wang, L.; Trippel, C.; Mendoza-Mendoza, A.; Ullmann, S.; Moretti, M.; Carsten, A.; Kahnt, J.; Reissmann, S.; Zechmann, B. et al.; Bange, G.; Kahmann, R.: The Ustilago maydis repetitive effector Rsp3 blocks the antifungal activity of mannose-binding maize proteins. NATURE COMMUNICATIONS 9, 1711 (2018)

Matsuda, H.; Mullapudi, S. T.; Yang, Y. H. C.; Masaki, H.; Hesselson, D.; Stainier, D. Y. R.: Whole-Organism Chemical Screening Identifies Modulators of Pancreatic beta-Cell Function. DIABETES 67 (11), pp. 2268 - 2279 (2018)

Mullapudi, S. T.; Helker, C. S. M.; Boezio, G. L. M.; Maischein, H.-M.; Sokol, A. M.; Guenther, S.; Matsuda, H.; Kubicek, S.; Graumann, J.; Yang, Y. H. C. et al.; Stainier, D. Y. R.: Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists. ELIFE 7, e42209 (2018)

Preussner, J.; Zhong, J.; Sreenivasan, K.; Guenther, S.; Engleitner, T.; Kuenne, C.; Glatzel, M.; Rad, R.; Looso, M.; Braun, T. et al.; Kim, J.: Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype. CELL STEM CELL 23 (6), pp. 794 - + (2018)

Rasouli, S. J.; El-Brolosy, M.; Tsedeke, A. T.; Bensimon-Brito, A.; Ghanbari, P.; Maischein, H.-M.; Kuenne, C.; Stainier, D. Y.: The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling. ELIFE 7, e38889 (2018)

Riddell, M.; Nakayama, A.; Hikita, T.; Mirzapourshafiyi, F.; Kawamura, T.; Pasha, A.; Li, M.; Masuzawa, M.; Looso, M.; Steinbacher, T. et al.; Ebnet, K.; Potente, M.; Hirose, T.; Ohno, S.; Fleming, I.; Gattenloehner, S.; Aung, P. P.; Thuy, P.; Yamasaki, O.; Yanagi, T.; Umemura, H.; Nakayama, M.: aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability. NATURE COMMUNICATIONS 9, 5357 (2018)

Sarode, P.; Zheng, X.; Weigert, A.; Tretyn, A.; Guenther, S.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Savai, R.: Reprogramming of Tumor Associated Macrophages by Modulating Wnt beta-Catenin Signalling in Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)

Stone, O. A.; El-Brolosy, M.; Wilhelm, K.; Liu, X.; Romao, A. M.; Grillo, E.; Lai, J. K. H.; Guenther, S.; Jeratsch, S.; Kuenne, C. et al.; Lee, I.-C.; Braun, T.; Santoro, M. M.; Locasale, J. W.; Potente, M.; Stainier, D. Y. R.: Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. NATURE COMMUNICATIONS 9, 4077 (2018)

Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.: 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1. NATURE COMMUNICATIONS 9, 177 (2018)

Walton, E. M.; Cronan, M. R.; Cambier, C. J.; Rossi, A.; Marass, M.; Foglia, M. D.; Brewer, W. J.; Poss, K. D.; Stainier, D. Y. R.; Bertozzi, C. R. et al.; Tobin, D. M.: Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. CELL HOST & MICROBE 24 (4), pp. 514 - + (2018)

Wuest, S.; Droese, S.; Heidler, J.; Wittig, I.; Klockner, I.; Franko, A.; Bonke, E.; Guenther, S.; Gaertner, U.; Boettger, T. et al.; Braun, T.: Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the DlK1-Dio3 Mega Gene Cluster. CELL METABOLISM 27 (5), pp. 1026 - + (2018)