Publications of Timothy Warwick

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Gunther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell reports 41 (7) (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Gunther, S.; Senturk Cetin, N.; Warwick, T.; Cao, C. et al.; Boos, F.; Izquierdo Ponce, J.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pfluger-Muller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nature communications 13 (1), 6563 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Mueller, N.; Lopez, M.; Pflueger-Mueller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Guenther, S.; Weigert, A.; Geisslinger, G.; Luetjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. HYPERTENSION 79 (6), pp. 1216 - 1226 (2022)

Malacarne, P. F.; Bezzenberger, J.; Lopez, M.; Warwick, T.; Mueller, N.; Brandes, R. P.; Rezende, F.: Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (11), 5939 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, pp. 1023 - 1035 (2022)

Muller, N.; Warwick, T.; Noack, K.; Malacarne, P. F.; Cooper, A. J. L.; Weissmann, N.; Schroder, K.; Brandes, R. P.; Rezende, F.: Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Antioxidants (Basel, Switzerland) 11 (2), p. 434 (2022)

Hahner, F.; Moll, F.; Warwick, T.; Hebchen, D. M.; Buchmann, G. K.; Epah, J.; Abplanalp, W.; Schader, T.; Gunther, S.; Gilsbach, R. et al.; Brandes, R. P.; Schroder, K.: Nox4 promotes endothelial differentiation through chromatin remodeling. Redox biology 55, 102381 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Muller, N.; Lopez, M.; Pfluger-Muller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Gunther, S.; Weigert, A.; GeiSSlinger, G.; Lutjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (Dallas, Tex.: 1979) (2022)

Warwick, T.; Schulz, M. H.; Gilsbach, R.; Brandes, R. P.; Seuter, S.: Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Nucleic acids research (2022)

Warwick, T.; Seredinski, S.; Krause, N. M.; Bains, J. K.; Althaus, L.; Oo, J. A.; Bonetti, A.; Dueck, A.; Engelhardt, S.; Schwalbe, H. et al.; Leisegang, M. S.; Schulz, M. H.; Brandes, R. P.: A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions. Briefings in bioinformatics (2022)

Buchmann, G. K.; Schurmann, C.; Spaeth, M.; Abplanalp, W.; Tombor, L.; John, D.; Warwick, T.; Rezende, F.; Weigert, A.; Shah, A. M. et al.; Hansmann, M.-L.; Weissmann, N.; Dimmeler, S.; Schroder, K.; Brandes, R. P.: The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice. Redox biology 45, p. 102050 - 102050 (2021)

Warwick, T.; Schulz, M. H.; Guenther, S.; Gilsbach, R.; Neme, A.; Carlberg, C.; Brandes, R. P.; Seuter, S.: A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes. SCIENTIFIC REPORTS 11 (1), 6518 (2021)

Oo, J. A.; Irmer, B.; Guenther, S.; Warwick, T.; Palfi, K.; Ponce, J. I.; Teichmann, T.; Pflueger-Mueller, B.; Gilsbach, R.; Brandes, R. P. et al.; Leisegang, M. S.: ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting. SCIENTIFIC REPORTS 10 (1), 19079 (2020)

Buchmann, G. K.; Schurmann, C.; Warwick, T.; Schulz, M. H.; Spaeth, M.; Muller, O. J.; Schroder, K.; Jo, H.; Weissmann, N.; Brandes, R. P.: Deletion of NoxO1 limits atherosclerosis development in female mice. Redox biology 37, p. 101713 - 101713 (2020)