Publications of Thomas Boettger

Weiss, M.; Hettrich, S.; Hofmann, T.; Hachim, S.; Guenther, S.; Braun, T.; Boettger, T.: Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH. NUCLEIC ACIDS RESEARCH (2024)

Wu, F.; Li, X.; Looso, M.; Liu, H.; Ding, D.; Guenther, S.; Kuenne, C.; Liu, S.; Weissmann, N.; Boettger, T. et al.; Atzberger, A.; Kolahian, S.; Renz, H.; Offermanns, S.; Gaertner, U.; Potente, M.; Zhou, Y.; Yuan, X.; Braun, T.: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. NATURE GENETICS 55 (1), pp. 100 - + (2024)

Wagner, J. U. G.; Tombor, L. S.; Malacarne, P. F.; Kettenhausen, L.-M.; Panthel, J.; Kujundzic, H.; Manickam, N.; Schmitz, K.; Cipca, M.; Stilz, K. A. et al.; Fischer, A.; Muhly-Reinholz, M.; Abplanalp, W. T.; John, D.; Mohanta, S. K.; Weber, C.; Habenicht, A. J. R.; Buchmann, G. K.; Angendohr, S.; Amin, E.; Scherschel, K.; Kloecker, N.; Kelm, M.; Schuettler, D.; Clauss, S.; Guenther, S.; Boettger, T.; Braun, T.; Baer, C.; Pham, M.-D.; Krishnan, J.; Hille, S.; Mueller, O. J.; Bozoglu, T.; Kupatt, C.; Nardini, E.; Osmanagic-Myers, S.; Meyer, C.; Zeiher, A. M.; Brandes, R. P.; Luxan, G.; Dimmeler, S.: Aging impairs the neurovascular interface in the heart. SCIENCE 381 (6660), pp. 897 - 905 (2023)

Wu, F.; Li, X.; Looso, M.; Liu, H.; Ding, D.; Guenther, S.; Kuenne, C.; Liu, S.; Weissmann, N.; Boettger, T. et al.; Atzberger, A.; Kolahian, S.; Renz, H.; Offermanns, S.; Gaertner, U.; Potente, M.; Zhou, Y.; Yuan, X.; Braun, T.: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. NATURE GENETICS (2023; 55(1)), pp. 100 - 111 (2023)

Woods, M. L.; Weiss, A.; Sokol, A. M.; Graumann, J.; Boettger, T.; Richter, A. M.; Schermuly, R. T.; Dammann, R. H.: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. CANCER GENE THERAPY (2022)

Klockner, I.; Schutt, C.; Gerhardt, T.; Boettger, T.; Braun, T.: Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. NATURE COMMUNICATIONS 13 (1), 3180 (2022)

Engelhardt, S.; Dimmeler, S.; Heim, C.; Baer, C.; Boettger, T.; Boon, R.; Brandes, R. P.; Braun, T.; Dueck, A.; Gagneur, J. et al.; Grote, P.; Holdt, L. M.; Jae, N.; Krishnan, J.; Kupatt, C.; Laugwitz, K. -.; Leisegang, M. S.; Maegdefessel, L.; Meitinger, T.; Moretti, A.; Mueller-McNicoll, M.; Sattler, M.; Schnieke, A.; Schulz, M.; Schunkert, H.; Schwalbe, H.; Teupser, D.; Thum, T.; Weber, C.; Wittig, I.; Zarnack, K.: Noncoding RNA in the cardiovascular system Collaborative research centre/transregio (SFB-TRR 267). KARDIOLOGE 16 (2), pp. 100 - 108 (2022)

Uenaka, M.; Yamashita, E.; Kikuta, J.; Morimoto, A.; Ao, T.; Mizuno, H.; Furuya, M.; Hasegawa, T.; Tsukazaki, H.; Sudo, T. et al.; Nishikawa, K.; Okuzaki, D.; Motooka, D.; Kosaka, N.; Sugihara, F.; Boettger, T.; Braun, T.; Ochiya, T.; Ishii, M.: Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo. NATURE COMMUNICATIONS 13 (1), 1066 (2022)

Valussi, M.; Besser, J.; Wystub-Lis, K.; Zukunft, S.; Richter, M.; Kubin, T.; Boettger, T.; Braun, T.: Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. SCIENCE ADVANCES 7 (42), eabi6648 (2021)

Wang, L.; Rice, M.; Swist, S.; Kubin, T.; Wu, F.; Wang, S.; Kraut, S.; Weissmann, N.; Boettger, T.; Wheeler, M. et al.; Schneider, A.; Braun, T.: BMP9 and BMP10 Act Directly on Vascular Smooth Muscle Cells for Generation and Maintenance of the Contractile State. CIRCULATION 143 (14), pp. 1394 - 1410 (2021)

Schutt, C.; Hallmann, A.; Hachim, S.; Klockner, I.; Valussi, M.; Atzberger, A.; Graumann, J.; Braun, T.; Boettger, T.: Linc-MYHconfiguresINO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy. EMBO JOURNAL 39 (22), e105098 (2020)

Li, M.; Nishio, S.-y.; Naruse, C.; Riddell, M.; Sapski, S.; Katsuno, T.; Hikita, T.; Mizapourshafiyi, F.; Smith, F. M.; Cooper, L. T. et al.; Lee, M. G.; Asano, M.; Boettger, T.; Krueger, M.; Wietelmann, A.; Graumann, J.; Day, B. W.; Boyd, A. W.; Offermanns, S.; Kitajiri, S.-i.; Usami, S.-i.; Nakayama, M.: Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. NATURE COMMUNICATIONS 11 (1), 1343 (2020)

Richter, A. M.; Woods, M. L.; Kuester, M. M.; Walesch, S. K.; Braun, T.; Boettger, T.; Dammann, R. H.: RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice. ONCOGENE 39 (15), pp. 3114 - 3127 (2020)

Christensen, S. T.; Johansson, S. E.; Warfvinge, K.; Braun, T.; Boettger, T.; Edvinsson, L.; Haanes, K. A.: Exploration of Physiological and Pathophysiological Implications of miRNA-143 and miRNA-145 in Cerebral Arteries. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 74 (5), pp. 409 - 419 (2019)

Deutschmeyer, V.; Breuer, J.; Walesch, S. K.; Sokol, A. M.; Graumann, J.; Bartkuhn, M.; Boettger, T.; Rossbach, O.; Richter, A. M.: Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function. CLINICAL EPIGENETICS 11 (1), 182 (2019)

Jia, Y.; Vong, J. S.-L.; Asafova, A.; Garvalov, B. K.; Caputo, L.; Cordero, J.; Singh, A.; Boettger, T.; Guenther, S.; Fink, L. et al.; Acker, T.; Barreto, G.; Seeger, W.; Braun, T.; Savai, R.; Dobreva, G.: Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET. JOURNAL OF EXPERIMENTAL MEDICINE 216 (6), pp. 1377 - 1395 (2019)

Bergmaier, P.; Weth, O.; Dienstbach, S.; Boettger, T.; Galjart, N.; Mernberger, M.; Bartkuhn, M.; Renkawitz, R.: Choice of binding sites for CTCFL compared to CTCF is driven by chromatin and by sequence preference. NUCLEIC ACIDS RESEARCH 46 (14), pp. 7097 - 7107 (2018)

Holmberg, J.; Bhattachariya, A.; Alajbegovic, A.; Rippe, C.; Ekman, M.; Dahan, D.; Tran Hien, T.; Boettger, T.; Braun, T.; Swaerd, K. et al.; Hellstrand, P.; Albinsson, S.: Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 38 (2), pp. 414 - 424 (2018)

Wuest, S.; Droese, S.; Heidler, J.; Wittig, I.; Klockner, I.; Franko, A.; Bonke, E.; Guenther, S.; Gaertner, U.; Boettger, T. et al.; Braun, T.: Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the DlK1-Dio3 Mega Gene Cluster. CELL METABOLISM 27 (5), pp. 1026 - + (2018)

Byskov, K.; Boettger, T.; Ruehle, P. F.; Nielsen, N. V.; Etscheid, M.; Kanse, S. M.: Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells. ATHEROSCLEROSIS 265, pp. 133 - 139 (2017)