Publications of Stefan Guenther

Cencioni, C.; Heid, J.; Krepelova, A.; Rasa, S. M. M.; Kuenne, C.; Guenther, S.; Baumgart, M.; Cellerino, A.; Neri, F.; Spallotta, F. et al.; Gaetano, C.: Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle. CELLS 8 (10), 1169 (2019)

Collins, M. M.; Ahlberg, G.; Hansen, C. V.; Guenther, S.; Marin-Juez, R.; Sokol, A. M.; El-Sammak, H.; Piesker, J.; Hellsten, Y.; Olesen, M. S. et al.; Stainier, D. Y. R.; Lundegaard, P. R.: Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (48), pp. 24115 - 24121 (2019)

Cremer, S.; Michalik, K. M.; Fischer, A.; Pfisterer, L.; Jae, N.; Winter, C.; Boon, R. A.; Muhly-Reinholz, M.; John, D.; Uchida, S. et al.; Weber, C.; Poller, W.; Guenther, S.; Braun, T.; Li, D. Y.; Maegdefessel, L.; Matic, L. P.; Hedin, U.; Soehnlein, O.; Zeiher, A.; Dimmeler, S.: Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. CIRCULATION 139 (10), pp. 1320 - 1334 (2019)

Di Tacchio, M.; Macas, J.; Weissenberger, J.; Sommer, K.; Baehr, O.; Steinbach, J. P.; Senft, C.; Seifert, V.; Glas, M.; Herrlinger, U. et al.; Krex, D.; Meinhardt, M.; Weyerbrock, A.; Timmer, M.; Goldbrunner, R.; Deckert, M.; Scheel, A. H.; Buettner, R.; Grauer, O. M.; Schittenhelm, J.; Tabatabai, G.; Harter, P. N.; Guenther, S.; Devraj, K.; Plate, K. H.; Reiss, Y.: Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF. CANCER IMMUNOLOGY RESEARCH 7 (12), pp. 1910 - 1927 (2019)

El-Brolosy, M. A.; Kontarakis, Z.; Rossi, A.; Kuenne, C.; Guenther, S.; Fukuda, N.; Kikhi, K.; Boezio, G. L. M.; Takacs, C. M.; Lai, S.-L. et al.; Fukuda, R.; Gerri, C.; Giraldez, A. J.; Stainier, D. Y. R.: Genetic compensation triggered by mutant mRNA degradation. NATURE 568 (7751), pp. 193 - + (2019)

Gao, R.; Liang, X.; Cheedipudi, S.; Cordero, J.; Jiang, X.; Zhang, Q.; Caputo, L.; Guenther, S.; Kuenne, C.; Ren, Y. et al.; Bhattacharya, S.; Yuan, X.; Barreto, G.; Chen, Y.; Braun, T.; Evans, S. M.; Sun, Y.; Dobreva, G.: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate. CELL RESEARCH 29 (6), pp. 486 - 501 (2019)

Iring, A.; Jin, Y.-J.; Albarran-Juarez, J.; Siragusa, M.; Wang, S.; Dancs, P. T.; Nakayama, A.; Tonack, S.; Chen, M.; Kuenne, C. et al.; Sokol, A. M.; Guenther, S.; Martinez, A.; Fleming, I.; Wettschureck, N.; Graumann, J.; Weinstein, L. S.; Offermanns, S.: Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. JOURNAL OF CLINICAL INVESTIGATION 129 (7), pp. 2775 - 2791 (2019)

Jia, Y.; Vong, J. S.-L.; Asafova, A.; Garvalov, B. K.; Caputo, L.; Cordero, J.; Singh, A.; Boettger, T.; Guenther, S.; Fink, L. et al.; Acker, T.; Barreto, G.; Seeger, W.; Braun, T.; Savai, R.; Dobreva, G.: Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET. JOURNAL OF EXPERIMENTAL MEDICINE 216 (6), pp. 1377 - 1395 (2019)

Kim, H.-T.; Yin, W.; Nakamichi, Y.; Panza, P.; Grohmann, B.; Buettner, C.; Guenther, S.; Ruppert, C.; Kobayashi, Y.; Guenther, A. et al.; Stainier, D. Y. R.: WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (51), pp. 25697 - 25706 (2019)

Leisegang, M. S.; Bibli, S.-I.; Guenther, S.; Pflueger-Mueller, B.; Oo, J. A.; Hoeper, C.; Seredinski, S.; Yekelchyk, M.; Schmitz-Rixen, T.; Schuermann, C. et al.; Hu, J.; Looso, M.; Sigala, F.; Boon, R. A.; Fleming, I.; Brandes, R. P.: Pleiotropic effects of laminar flow and statins depend on the Kruppel-like factor-induced lncRNA MANTIS. EUROPEAN HEART JOURNAL 40 (30), pp. 2523 - 2533 (2019)

Leisegang, M. S.; Gu, L.; Preussner, J.; Guenther, S.; Hitzel, J.; Ratiu, C.; Weigert, A.; Chen, W.; Schwarz, E. C.; Looso, M. et al.; Fork, C.; Brandes, R. P.: The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G. FEBS LETTERS 593 (5), pp. 487 - 498 (2019)

Marass, M.; Beisaw, A.; Gerri, C.; Luzzani, F.; Fukuda, N.; Gunther, S.; Kuenne, C.; Reischauer, S.; Stainier, D. Y. R.: Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish. DEVELOPMENT 146 (11), UNSP dev173427 (2019)

Rubio, K.; Singh, I.; Dobersch, S.; Sarvari, P.; Guenther, S.; Cordero, J.; Mehta, A.; Wujak, L.; Cabrera-Fuentes, H.; Chao, C.-M. et al.; Braubach, P.; Bellusci, S.; Seeger, W.; Guenther, A.; Preissner, K. T.; Wygrecka, M.; Savai, R.; Papy-Garcia, D.; Dobreva, G.; Heikenwalder, M.; Savai-Pullamsetti, S.; Braun, T.; Barreto, G.: Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. NATURE COMMUNICATIONS 10, 2229 (2019)

Salwig, I.; Spitznagel, B.; Vazquez-Armendariz, A. I.; Khalooghi, K.; Guenther, S.; Herold, S.; Szibor, M.; Braun, T.: Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo. EMBO JOURNAL 38 (12), e102099 (2019)

Schlegel, J.; Hoffmann, J.; Roell, D.; Mueller, B.; Guenther, S.; Zhang, W.; Janise, A.; Voessing, C.; Fuehler, B.; Neidhardt, J. et al.; Khanna, H.; Lorenz, B.; Stieger, K.: Toward genome editing in X-linked RP-development of a mouse model with specific treatment relevant features. TRANSLATIONAL RESEARCH 203, pp. 57 - 72 (2019)

Schuermann, C.; Dienst, F. L.; Palfi, K.; Vasconez, A. E.; Oo, J. A.; Wang, S.; Buchmann, G. K.; Offermanns, S.; van de Sluis, B.; Leisegang, M. S. et al.; Guenther, S.; Humbert, P. O.; Lee, E.; Zhu, J.; Weigert, A.; Mathoor, P.; Wittig, I.; Kruse, C.; Brandes, R. P.: The polarity protein Scrib limits atherosclerosis development in mice. CARDIOVASCULAR RESEARCH 115 (14), pp. 1963 - 1974 (2019)

Yekelchyk, M.; Guenther, S.; Preussner, J.; Braun, T.: Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population. BASIC RESEARCH IN CARDIOLOGY 114 (5), 36 (2019)

Brandt, C.; Nolte, H.; Henschke, S.; Ruud, L. E.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Guenther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krueger, M.; Bruening, J. C.: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. CELL 175 (5), pp. 1321 - + (2018)

Cencioni, C.; Spallotta, F.; Savoia, M.; Kuenne, C.; Guenther, S.; Re, A.; Wingert, S.; Rehage, M.; Sueruen, D.; Siragusa, M. et al.; Smith, J. G.; Schnuetgen, F.; von Melchner, H.; Rieger, M. A.; Martelli, F.; Riccio, A.; Fleming, I.; Braun, T.; Zeiher, A. M.; Farsetti, A.; Gaetano, C.: Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells. NATURE COMMUNICATIONS 9, 1281 (2018)

Gauvrit, S.; Villasenor, A.; Strilic, B.; Kitchen, P.; Collins, M. M.; Marin-Juez, R.; Guenther, S.; Maischein, H.-M.; Fukuda, N.; Canham, M. A. et al.; Brickman, J. M.; Bogue, C. W.; Jayaraman, P.-S.; Stainier, D. Y. R.: HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development. NATURE COMMUNICATIONS 9, 2704 (2018)