Publications of IMPRS students

Ali, Z.; Mukwaya, A.; Biesemeier, A.; Ntzouni, M.; Ramskold, D.; Giatrellis, S.; Mammadzada, P.; Cao, R.; Lennikov, A.; Marass, M. et al.; Gerri, C.; Hildesjo, C.; Taylor, M.; Deng, Q.; Peebo, B.; del Peso, L.; Kvanta, A.; Sandberg, R.; Schraermeyer, U.; Andre, H.; Steffensen, J. F.; Lagali, N.; Cao, Y.; Kele, J.; Dahl Jensen, L.: Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 39 (7), pp. 1402 - 1418 (2019)

Chennupati, R.; Wirth, A.; Favre, J.; Li, R.; Bonnavion, R.; Jin, Y.-J.; Wietelmann, A.; Schweda, F.; Wettschureck, N.; Henrion, D. et al.; Offermanns, S.: Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance. ELIFE 8, e49374 (2019)

Collins, M. M.; Ahlberg, G.; Hansen, C. V.; Guenther, S.; Marin-Juez, R.; Sokol, A. M.; El-Sammak, H.; Piesker, J.; Hellsten, Y.; Olesen, M. S. et al.; Stainier, D. Y. R.; Lundegaard, P. R.: Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (48), pp. 24115 - 24121 (2019)

D'Aniello, E.; Fellous, T.; Iannotti, F. A.; Gentile, A.; Allara, M.; Balestrieri, F.; Gray, R.; Amodeo, P.; Vitale, R. M.; Di Marzo, V.: Identification and characterization of phytocannabinoids as novel dual PPAR alpha/gamma agonists by a computational and in vitro experimental approach. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1863 (3), pp. 586 - 597 (2019)

El-Brolosy, M. A.; Kontarakis, Z.; Rossi, A.; Kuenne, C.; Guenther, S.; Fukuda, N.; Kikhi, K.; Boezio, G. L. M.; Takacs, C. M.; Lai, S.-L. et al.; Fukuda, R.; Gerri, C.; Giraldez, A. J.; Stainier, D. Y. R.: Genetic compensation triggered by mutant mRNA degradation. NATURE 568 (7751), pp. 193 - + (2019)

Fukuda, R.; Aharonov, A.; Ong, Y. T.; Stone, O. A.; El-Brolosy, M.; Maischein, H.-M.; Potente, M.; Tzahor, E.; Stainier, D. Y. R.: Metabolic modulation regulates cardiac wall morphogenesis in zebrafish. ELIFE 8, e50161 (2019)

Fukuda, R.; Gunawan, F.; Ramadass, R.; Beisaw, A.; Konzer, A.; Mullapudi, S. T.; Gentile, A.; Maischein, H.-M.; Graumann, J.; Stainier, D. Y. R.: Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis. DEVELOPMENTAL CELL 51 (1), pp. 62 - + (2019)

Giordani, L.; He, G. J.; Negroni, E.; Sakai, H.; Law, J. Y. C.; Siu, M. M.; Wan, R.; Corneau, A.; Tajbakhsh, S.; Cheung, T. H. et al.; Le Grand, F.: High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations. MOLECULAR CELL 74 (3), pp. 609 - + (2019)

Gunawan, F.; Gentile, A.; Fukuda, R.; Tsedeke, A. T.; Jimenez-Amilburu, V.; Ramadass, R.; Iida, A.; Sehara-Fujisawa, A.; Stainier, D. Y. R.: Focal adhesions are essential to drive zebrafish heart valve morphogenesis. JOURNAL OF CELL BIOLOGY 218 (3), pp. 1039 - 1054 (2019)

Helker, C. S. M.; Mullapudi, S.-T.; Mueller, L. M.; Preussner, J.; Tunaru, S.; Skog, O.; Kwon, H.-B.; Kreuder, F.; Lancman, J. J.; Bonnavion, R. et al.; Dong, P. D. S.; Looso, M.; Offermanns, S.; Korsgren, O.; Spagnoli, F. M.; Stainier, D. Y. R.: A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development. DEVELOPMENT 146 (14), UNSP dev172569 (2019)

Jha, S. K.; Rauniyar, K.; Chronowska, E.; Mattonet, K.; Maina, E. W.; Koistinen, H.; Stenman, U.-H.; Alitalo, K.; Jeltsch, M.: KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. ELIFE 8, e44478 (2019)

Jia, Y.; Vong, J. S.-L.; Asafova, A.; Garvalov, B. K.; Caputo, L.; Cordero, J.; Singh, A.; Boettger, T.; Guenther, S.; Fink, L. et al.; Acker, T.; Barreto, G.; Seeger, W.; Braun, T.; Savai, R.; Dobreva, G.: Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET. JOURNAL OF EXPERIMENTAL MEDICINE 216 (6), pp. 1377 - 1395 (2019)

Jimenez-Amilburu, V.; Stainier, D. Y. R.: The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish. DEVELOPMENT 146 (9), UNSP dev171207 (2019)

Lai, J. K. H.; Gagalova, K. K.; Kuenne, C.; El-Brolosy, M. A.; Stainier, D. Y. R.: Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish. DEVELOPMENTAL BIOLOGY 454 (1), pp. 21 - 28 (2019)

Leisegang, M. S.; Bibli, S.-I.; Guenther, S.; Pflueger-Mueller, B.; Oo, J. A.; Hoeper, C.; Seredinski, S.; Yekelchyk, M.; Schmitz-Rixen, T.; Schuermann, C. et al.; Hu, J.; Looso, M.; Sigala, F.; Boon, R. A.; Fleming, I.; Brandes, R. P.: Pleiotropic effects of laminar flow and statins depend on the Kruppel-like factor-induced lncRNA MANTIS. EUROPEAN HEART JOURNAL 40 (30), pp. 2523 - 2533 (2019)

Marass, M.; Beisaw, A.; Gerri, C.; Luzzani, F.; Fukuda, N.; Gunther, S.; Kuenne, C.; Reischauer, S.; Stainier, D. Y. R.: Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish. DEVELOPMENT 146 (11), UNSP dev173427 (2019)

Marin-Juez, R.; El-Sammak, H.; Helker, C. S. M.; Kamezaki, A.; Mullapuli, S. T.; Bibli, S.-I.; Foglia, M. J.; Fleming, I.; Poss, K. D.; Stainier, D. Y. R.: Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. DEVELOPMENTAL CELL 51 (4), pp. 503 - + (2019)

Merz, S. F.; Korste, S.; Bornemann, L.; Michel, L.; Stock, P.; Squire, A.; Soun, C.; Engel, D. R.; Detzer, J.; Loerchner, H. et al.; Hermann, D. M.; Kamler, M.; Klode, J.; Hendgen-Cotta, U. B.; Rassaf, T.; Gunzer, M.; Totzeck, M.: Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response. NATURE COMMUNICATIONS 10, 2312 (2019)

Mullapudi, S. T.; Boezio, G. L. M.; Rossi, A.; Marass, M.; Matsuoka, R. L.; Matsuda, H.; Helker, C. S. M.; Yang, Y. H. C.; Stainier, D. Y. R.: Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function. DEVELOPMENT 146 (21), dev173674 (2019)

Preussner, J.; Zhong, J.; Looso, M.; Braun, T.; Kim, J.: Connect-four: genomic analyses of regenerating stem cells identifies zygotic Dux factors as tumor initiators. MOLECULAR & CELLULAR ONCOLOGY 6 (2), e1565469 (2019)

Salwig, I.; Spitznagel, B.; Vazquez-Armendariz, A. I.; Khalooghi, K.; Guenther, S.; Herold, S.; Szibor, M.; Braun, T.: Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo. EMBO JOURNAL 38 (12), e102099 (2019)

Solimani, F.; Pollmann, R.; Schmidt, T.; Schmidt, A.; Zheng, X.; Savai, R.; Muehlenbein, S.; Pickert, J.; Eubel, V.; Moebs, C. et al.; Eming, R.; Hertl, M.: Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus. FRONTIERS IN IMMUNOLOGY 10, 1808 (2019)

Yang, L.; Joseph, S.; Sun, T.; Hoffmann, J.; Thevissen, S.; Offermanns, S.; Strilic, B.: TAK1 regulates endothelial cell necroptosis and tumor metastasis. CELL DEATH AND DIFFERENTIATION 26 (10), pp. 1987 - 1997 (2019)

Yekelchyk, M.; Guenther, S.; Preussner, J.; Braun, T.: Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population. BASIC RESEARCH IN CARDIOLOGY 114 (5), 36 (2019)

Yin, W.; Kim, H.-T.; Wang, S.; Gunawan, F.; Li, R.; Buettner, C.; Grohmann, B.; Sengle, G.; Sinner, D.; Offermanns, S. et al.; Stainier, D. Y. R.: Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. EUROPEAN RESPIRATORY JOURNAL 53 (3), 1800840 (2019)