Publications of Stefan Guenther

Nakayama, A.; Roquid, K. A.; Iring, A.; Strilic, B.; Guenther, S.; Chen, M.; Weinstein, L. S.; Offermanns, S.: Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth. JOURNAL OF EXPERIMENTAL MEDICINE 220 (1), e20211628 (2023)

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Gunther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell reports 41 (7) (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Gunther, S.; Senturk Cetin, N.; Warwick, T.; Cao, C. et al.; Boos, F.; Izquierdo Ponce, J.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pfluger-Muller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nature communications 13 (1), 6563 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Mattonet, K.; Riemslagh, F. W.; Guenther, S.; Prummel, K. D.; Kesavan, G.; Hans, S.; Ebersberger, I.; Brand, M.; Burger, A.; Reischauer, S. et al.; Mosimann, C.; Stainier, D. Y. R.: Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. SCIENCE ADVANCES 8 (35), eabn2082 (2022)

Georgieva, A. M.; Guo, X.; Bartkuhn, M.; Guenther, S.; Kuenne, C.; Smolka, C.; Atzberger, A.; Gaertner, U.; Mamchaoui, K.; Bober, E. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. NATURE COMMUNICATIONS 13 (1), 4184 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Mueller, N.; Lopez, M.; Pflueger-Mueller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Guenther, S.; Weigert, A.; Geisslinger, G.; Luetjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. HYPERTENSION 79 (6), pp. 1216 - 1226 (2022)

Liang, G.; Wang, S.; Shao, J.; Jin, Y.-J.; Xu, L.; Yan, Y.; Guenther, S.; Wang, L.; Offermanns, S.: Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. CIRCULATION RESEARCH 130 (11), pp. 1647 - 1659 (2022)

Peng, Y.; Du, J.; Gunther, S.; Guo, X.; Wang, S.; Schneider, A.; Zhu, L.; Braun, T.: Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells. REDOX BIOLOGY 52, 102309 (2022)

El-Sammak, H.; Yang, B.; Guenther, S.; Chen, W.; Marin-Juez, R.; Stainier, D. Y. R.: A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. CIRCULATION RESEARCH 130 (7), pp. 1014 - 1029 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, pp. 1023 - 1035 (2022)

Hahner, F.; Moll, F.; Warwick, T.; Hebchen, D. M.; Buchmann, G. K.; Epah, J.; Abplanalp, W.; Schader, T.; Gunther, S.; Gilsbach, R. et al.; Brandes, R. P.; Schroder, K.: Nox4 promotes endothelial differentiation through chromatin remodeling. Redox biology 55, 102381 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Muller, N.; Lopez, M.; Pfluger-Muller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Gunther, S.; Weigert, A.; GeiSSlinger, G.; Lutjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (Dallas, Tex.: 1979) (2022)

Ong, Y. T.; Andrade, J.; Armbruster, M.; Shi, C.; Castro, M.; Costa, A. S. H.; Sugino, T.; Eelen, G.; Zimmermann, B.; Wilhelm, K. et al.; Lim, J.; Watanabe, S.; Guenther, S.; Schneider, A.; Zanconato, F.; Kaulich, M.; Pan, D.; Braun, T.; Gerhardt, H.; Efeyan, A.; Carmeliet, P.; Piccolo, S.; Grosso, A. R.; Potente, M.: A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. NATURE METABOLISM 4 (6), pp. 672 - 682 (2022)

Tarasco, M.; Gavaia, P. J.; Bensimon-Brito, A.; Cardeira-da-Silva, J.; Ramkumar, S.; Cordelieres, F. P.; Guenther, S.; Bebianno, M. J.; Stainier, D. Y. R.; Cancela, M. L. et al.; Laize, V.: New insights into benzo[alpha]pyrene osteotoxicity in zebrafish. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 226, 112838 (2021)

Gurusamy, M.; Tischner, D.; Shao, J.; Klatt, S.; Zukunft, S.; Bonnavion, R.; Guenther, S.; Siebenbrodt, K.; Kestner, R.-I.; Kuhlmann, T. et al.; Fleming, I.; Offermanns, S.; Wettschureck, N.: G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS 12 (1), 6798 (2021)

Qi, H.; Liu, H.; Pullamsetti, S. S.; Gunther, S.; Kuenne, C.; Atzberger, A.; Sommer, N.; Hadzic, S.; Gunther, A.; Weissmann, N. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. CIRCULATION 144 (13), pp. 1042 - 1058 (2021)

Allanki, S.; Strilic, B.; Scheinberger, L.; Onderwater, Y. L.; Marks, A.; Guenther, S.; Preussner, J.; Kikhi, K.; Looso, M.; Stainier, D. Y. R. et al.; Reischauer, S.: Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. SCIENCE ADVANCES 7 (37), eabg6497 (2021)

Tsedeke, A. T.; Allanki, S.; Gentile, A.; Jimenez-Amilburu, V.; Rasouli, S. J.; Guenther, S.; Lai, S.-L.; Stainier, D. Y. R.; Marin-Juez, R.: Cardiomyocyte heterogeneity during zebrafish development and regeneration. DEVELOPMENTAL BIOLOGY 476, pp. 259 - 271 (2021)